St. John’s WortAugust 16, 2007 6:20 pm natural cures, sunburn, sunburn remedy
Most clinical signs of the wort are caused by photosensitisation. Plants may induce photosensitisation from chemicals contained in ingested plants, or secondary photosensitisation from plant-associated damage to the liver. Araya and Ford explored changes in liver function and concluded there was no evidence of Hypericum-related effect on the excretory capacity of the liver, or any interference was minimal and temporary. However at high and continuous dose rates changes in blood plasma indicative of some liver damage have been observed.
Photosensitisation causes skin inflammation by a mechanism involving a pigment or photodynamic compound, which when activated by a certain wavelength of light leads to oxidation reactions in vivo. This leads to lesions of tissue, particularly noticeable on and around parts of skin exposed to light. Lightly covered or poorly pigmented areas are most conspicuous. Removal of affected animals from sunlight results in reduced symptoms of poisoning.